HIV-1 integrase crosslinked oligomers are active in vitro

The oligomeric state of active human immunodeficiency virus type 1 (HIV-1) integrase (IN) has not been clearly elucidated. We analyzed the activity of the different purified oligomeric forms of recombinant IN obtained after stabilization by platinum crosslinking. The crosslinked tetramer isolated by...

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Main Authors: Faure, Aurélie, Calmels, Christina, Desjobert, Cécile, Castroviejo, Michel, Caumont-Sarcos, Anne, Tarrago-Litvak, Laura, Litvak, Simon, Parissi, Vincent
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2005
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC549407/
https://ncbi.nlm.nih.gov/pubmed/15718297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki241
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