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Functional Coupling between HIV-1 Integrase and the SWI/SNF Chromatin Remodeling Complex for Efficient in vitro Integration into Stable Nucleosomes

Establishment of stable HIV-1 infection requires the efficient integration of the retroviral genome into the host DNA. The molecular mechanism underlying the control of this process by the chromatin structure has not yet been elucidated. We show here that stably associated nucleosomes strongly inhib...

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書誌詳細
主要な著者: Lesbats, Paul, Botbol, Yair, Chevereau, Guillaume, Vaillant, Cédric, Calmels, Christina, Arneodo, Alain, Andreola, Marie-Line, Lavigne, Marc, Parissi, Vincent
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037357/
https://ncbi.nlm.nih.gov/pubmed/21347347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001280
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