Functional Coupling between HIV-1 Integrase and the SWI/SNF Chromatin Remodeling Complex for Efficient in vitro Integration into Stable Nucleosomes

Establishment of stable HIV-1 infection requires the efficient integration of the retroviral genome into the host DNA. The molecular mechanism underlying the control of this process by the chromatin structure has not yet been elucidated. We show here that stably associated nucleosomes strongly inhib...

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Bibliographic Details
Main Authors: Lesbats, Paul, Botbol, Yair, Chevereau, Guillaume, Vaillant, Cédric, Calmels, Christina, Arneodo, Alain, Andreola, Marie-Line, Lavigne, Marc, Parissi, Vincent
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037357/
https://ncbi.nlm.nih.gov/pubmed/21347347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001280
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