G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells

Progression of mammalian cells through the G1 and S phases of the cell cycle is driven by D-type and E-type cyclins. According to the current models, at least one of these cyclin families must be present to allow cell proliferation. Here, we show that several cell types can proliferate in the absenc...

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Veröffentlicht in:Nat Cell Biol
Hauptverfasser: Liu, Lijun, Michowski, Wojciech, Inuzuka, Hiroyuki, Shimizu, Kouhei, Nihira, Naoe Taira, Chick, Joel M., Li, Na, Geng, Yan, Meng, Alice Y., Ordureau, Alban, Kolodziejczyk, Aleksandra, Ligon, Keith L., Bronson, Roderick T., Polyak, Kornelia, Harper, J. Wade, Gygi, Steven P., Wei, Wenyi, Sicinski, Piotr
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489757/
https://ncbi.nlm.nih.gov/pubmed/28192421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3474
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