G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells

Progression of mammalian cells through the G1 and S phases of the cell cycle is driven by D-type and E-type cyclins. According to the current models, at least one of these cyclin families must be present to allow cell proliferation. Here, we show that several cell types can proliferate in the absenc...

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Publicado no:Nat Cell Biol
Main Authors: Liu, Lijun, Michowski, Wojciech, Inuzuka, Hiroyuki, Shimizu, Kouhei, Nihira, Naoe Taira, Chick, Joel M., Li, Na, Geng, Yan, Meng, Alice Y., Ordureau, Alban, Kolodziejczyk, Aleksandra, Ligon, Keith L., Bronson, Roderick T., Polyak, Kornelia, Harper, J. Wade, Gygi, Steven P., Wei, Wenyi, Sicinski, Piotr
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489757/
https://ncbi.nlm.nih.gov/pubmed/28192421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3474
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