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Elongation Affinity, Activation Barrier, and Stability of Aβ42 Oligomers/Fibrils in Physiological Saline

Amyloid-beta (Aβ) peptides, Aβ40 and the more neurotoxic Aβ42, have been the subject of many research efforts for Alzheimer's disease. In two recent independent investigations, the atomistic structure of Aβ42 fibril has been clearly established in the S-shaped conformation consisting of three β...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Rodriguez, Roberto A, Chen, Liao Y, Plascencia-Villa, Germán, Perry, George
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489073/
https://ncbi.nlm.nih.gov/pubmed/28427941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.04.084
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