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Elongation Affinity, Activation Barrier, and Stability of Aβ42 Oligomers/Fibrils in Physiological Saline

Amyloid-beta (Aβ) peptides, Aβ40 and the more neurotoxic Aβ42, have been the subject of many research efforts for Alzheimer's disease. In two recent independent investigations, the atomistic structure of Aβ42 fibril has been clearly established in the S-shaped conformation consisting of three β...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biochem Biophys Res Commun
Egile Nagusiak: Rodriguez, Roberto A, Chen, Liao Y, Plascencia-Villa, Germán, Perry, George
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489073/
https://ncbi.nlm.nih.gov/pubmed/28427941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.04.084
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