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Thermodynamics of Amyloid-β Fibril Elongation: Atomistic Details of the Transition State
[Image: see text] Amyloid-β (Aβ) fibrils and plaques are one of the hallmarks of Alzheimer’s disease. While the kinetics of fibrillar growth of Aβ have been extensively studied, several vital questions remain. In particular, the atomistic origins of the Arrhenius barrier observed in experiments have...
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| Pubblicato in: | ACS Chem Neurosci |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American
Chemical
Society
2017
|
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5911799/ https://ncbi.nlm.nih.gov/pubmed/29239603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00409 |
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