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Polymorph-specific kinetics and thermodynamics of β-amyloid fibril growth

Amyloid fibrils formed by the 40-residue β-amyloid peptide (Aβ(1–40)) are highly polymorphic, with molecular structures that depend on the details of growth conditions. Underlying differences in physical properties are not well understood. Here, we investigate differences in growth kinetics and ther...

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Detalhes bibliográficos
Main Authors: Qiang, Wei, Kelley, Kevin, Tycko, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3686096/
https://ncbi.nlm.nih.gov/pubmed/23627695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja311963f
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