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Simulations of nucleation and elongation of amyloid fibrils
We present a coarse-grained model for the growth kinetics of amyloid fibrils from solutions of peptides and address the fundamental mechanism of nucleation and elongation by using a lattice Monte Carlo procedure. We reproduce the three main characteristics of nucleation of amyloid fibrils: (1) exist...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Institute of Physics
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2671213/ https://ncbi.nlm.nih.gov/pubmed/19173542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3050295 |
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