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Nucleation of Polymorphic Amyloid Fibrils

One and the same protein can self-assemble into amyloid fibrils with different morphologies. The phenomenon of fibril polymorphism is relevant biologically because different fibril polymorphs can have different toxicity, but there is no tool for predicting which polymorph forms and under what condit...

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Détails bibliographiques
Publié dans:Biophys J
Auteur principal: Auer, Stefan
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375620/
https://ncbi.nlm.nih.gov/pubmed/25762329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.01.013
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