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Computational Assembly of Polymorphic Amyloid Fibrils Reveals Stable Aggregates

Amyloid proteins aggregate into polymorphic fibrils that damage tissues of the brain, nerves, and heart. Experimental and computational studies have examined the structural basis and the nucleation of short fibrils, but the ability to predict and precisely quantify the stability of larger aggregates...

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Autores principales: Smaoui, Mohamed Raef, Poitevin, Frédéric, Delarue, Marc, Koehl, Patrice, Orland, Henri, Waldispühl, Jérôme
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566450/
https://ncbi.nlm.nih.gov/pubmed/23442919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.037
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