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Probing the binding affinity of amyloids to reduce toxicity of oligomers in diabetes
Motivation: Amyloids play a role in the degradation of β-cells in diabetes patients. In particular, short amyloid oligomers inject themselves into the membranes of these cells and create pores that disrupt the strictly controlled flow of ions through the membranes. This leads to cell death. Getting...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4495297/ https://ncbi.nlm.nih.gov/pubmed/25777526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv143 |
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