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Computational Assembly of Polymorphic Amyloid Fibrils Reveals Stable Aggregates

Amyloid proteins aggregate into polymorphic fibrils that damage tissues of the brain, nerves, and heart. Experimental and computational studies have examined the structural basis and the nucleation of short fibrils, but the ability to predict and precisely quantify the stability of larger aggregates...

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Dettagli Bibliografici
Autori principali: Smaoui, Mohamed Raef, Poitevin, Frédéric, Delarue, Marc, Koehl, Patrice, Orland, Henri, Waldispühl, Jérôme
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566450/
https://ncbi.nlm.nih.gov/pubmed/23442919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.12.037
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