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Design and Characterization of Chemically Stabilized Aβ42 Oligomers

A popular working hypothesis of Alzheimer’s disease causation is amyloid β-protein oligomers are the key neuropathogenetic agents. Rigorously elucidating the role of oligomers requires the production of stable oligomers of each size. We previously used zero-length photochemical cross-linking to allo...

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Dades bibliogràfiques
Publicat a:Biochemistry
Autors principals: Yamin, Ghiam, Huynh, Tien-Phat Vuong, Teplow, David B.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104494/
https://ncbi.nlm.nih.gov/pubmed/26241378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00318
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