Dapagliflozin suppresses glucagon signaling in rodent models of diabetes

Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a class of antidiabetic drug used for the treatment of diabetes. These drugs are thought to lower blood glucose by blocking reabsorption of glucose by SGLT2 in the proximal convoluted tubules of the kidney. To investigate the effect of inhibiting...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Wang, May-yun, Yu, Xinxin, Lee, Young, McCorkle, Sara Kay, Chen, Shiuhwei, Li, Jianping, Wang, Zhao V., Davidson, Jaime A., Scherer, Philipp E., Holland, William L., Unger, Roger H., Roth, Michael G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2017
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488956/
https://ncbi.nlm.nih.gov/pubmed/28584109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705845114
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