Dapagliflozin suppresses glucagon signaling in rodent models of diabetes

Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a class of antidiabetic drug used for the treatment of diabetes. These drugs are thought to lower blood glucose by blocking reabsorption of glucose by SGLT2 in the proximal convoluted tubules of the kidney. To investigate the effect of inhibiting...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Wang, May-yun, Yu, Xinxin, Lee, Young, McCorkle, Sara Kay, Chen, Shiuhwei, Li, Jianping, Wang, Zhao V., Davidson, Jaime A., Scherer, Philipp E., Holland, William L., Unger, Roger H., Roth, Michael G.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488956/
https://ncbi.nlm.nih.gov/pubmed/28584109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705845114
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