Dapagliflozin suppresses glucagon signaling in rodent models of diabetes

Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a class of antidiabetic drug used for the treatment of diabetes. These drugs are thought to lower blood glucose by blocking reabsorption of glucose by SGLT2 in the proximal convoluted tubules of the kidney. To investigate the effect of inhibiting...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, May-yun, Yu, Xinxin, Lee, Young, McCorkle, Sara Kay, Chen, Shiuhwei, Li, Jianping, Wang, Zhao V., Davidson, Jaime A., Scherer, Philipp E., Holland, William L., Unger, Roger H., Roth, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488956/
https://ncbi.nlm.nih.gov/pubmed/28584109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705845114
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