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12-HETrE, a 12-LOX oxylipin of DGLA, inhibits thrombosis via Gα(s) signaling in platelets
OBJECTIVE: Dietary supplementation with polyunsaturated fatty acids (PUFAs) has been widely used for primary and secondary prevention of CVD in individuals at risk; however, the cardioprotective benefits of PUFAs remain controversial due to lack of mechanistic and in vivo evidence. We present direct...
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| Publié dans: | Arterioscler Thromb Vasc Biol |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5488693/ https://ncbi.nlm.nih.gov/pubmed/27470510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308050 |
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