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DHA 12-LOX-derived oxylipins regulate platelet activation and thrombus formation through a PKA-dependent signaling pathway
BACKGROUND: The effects of the docosahexaenoic acid (DHA) on cardiovascular disease are controversial and a mechanistic understanding of how this ω-3 polyunsaturated fatty (ω-3 PUFA) regulates platelet reactivity and the subsequent risk of a thrombotic event is warranted. In platelets, DHA is oxidiz...
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| Publicado no: | J Thromb Haemost |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7925359/ https://ncbi.nlm.nih.gov/pubmed/33222370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.15184 |
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