12-HETrE, a 12-LOX oxylipin of DGLA, inhibits thrombosis via Gα(s) signaling in platelets

OBJECTIVE: Dietary supplementation with polyunsaturated fatty acids (PUFAs) has been widely used for primary and secondary prevention of CVD in individuals at risk; however, the cardioprotective benefits of PUFAs remain controversial due to lack of mechanistic and in vivo evidence. We present direct...

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Publicat a:Arterioscler Thromb Vasc Biol
Autors principals: Yeung, Jennifer, Tourdot, Benjamin E., Adili, Reheman, Green, Abigail R., Freedman, Cody J., Fernandez-Perez, Pilar, Yu, Johnny, Holman, Theodore R., Holinstat, Michael
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488693/
https://ncbi.nlm.nih.gov/pubmed/27470510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308050
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