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BRIE: transcriptome-wide splicing quantification in single cells

Single-cell RNA-seq (scRNA-seq) provides a comprehensive measurement of stochasticity in transcription, but the limitations of the technology have prevented its application to dissect variability in RNA processing events such as splicing. Here, we present BRIE (Bayesian regression for isoform estima...

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Detalles Bibliográficos
Publicado en:Genome Biol
Main Authors: Huang, Yuanhua, Sanguinetti, Guido
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488362/
https://ncbi.nlm.nih.gov/pubmed/28655331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1248-5
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