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BRIE: transcriptome-wide splicing quantification in single cells

Single-cell RNA-seq (scRNA-seq) provides a comprehensive measurement of stochasticity in transcription, but the limitations of the technology have prevented its application to dissect variability in RNA processing events such as splicing. Here, we present BRIE (Bayesian regression for isoform estima...

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Bibliografski detalji
Izdano u:Genome Biol
Glavni autori: Huang, Yuanhua, Sanguinetti, Guido
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488362/
https://ncbi.nlm.nih.gov/pubmed/28655331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1248-5
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