From single-cell to cell-pool transcriptomes: Stochasticity in gene expression and RNA splicing

Single-cell RNA-seq mammalian transcriptome studies are at an early stage in uncovering cell-to-cell variation in gene expression, transcript processing and editing, and regulatory module activity. Despite great progress recently, substantial challenges remain, including discriminating biological va...

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Main Authors: Marinov, Georgi K., Williams, Brian A., McCue, Ken, Schroth, Gary P., Gertz, Jason, Myers, Richard M., Wold, Barbara J.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2014
Teme:
Method
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941114/
https://ncbi.nlm.nih.gov/pubmed/24299736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.161034.113
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