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Melissa: Bayesian clustering and imputation of single-cell methylomes
Measurements of single-cell methylation are revolutionizing our understanding of epigenetic control of gene expression, yet the intrinsic data sparsity limits the scope for quantitative analysis of such data. Here, we introduce Melissa (MEthyLation Inference for Single cell Analysis), a Bayesian hie...
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| Publicat a: | Genome Biol |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6427844/ https://ncbi.nlm.nih.gov/pubmed/30898142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1665-8 |
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