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scMET: Bayesian modeling of DNA methylation heterogeneity at single-cell resolution
High-throughput single-cell measurements of DNA methylomes can quantify methylation heterogeneity and uncover its role in gene regulation. However, technical limitations and sparse coverage can preclude this task. scMET is a hierarchical Bayesian model which overcomes sparsity, sharing information a...
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| Publicado no: | Genome Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8056718/ https://ncbi.nlm.nih.gov/pubmed/33879195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-021-02329-8 |
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