Multi-omics profiling of mouse gastrulation at single cell resolution

Formation of the three primary germ layers during gastrulation is an essential step in the establishment of the vertebrate body plan and is associated with major transcriptional changes(1–5). Global epigenetic reprogramming accompanies these changes(6–8), but the role of the epigenome in regulating...

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Veröffentlicht in:Nature
Hauptverfasser: Argelaguet, Ricard, Clark, Stephen J, Mohammed, Hisham, Stapel, L Carine, Krueger, Christel, Kapourani, Chantriolnt-Andreas, Imaz-Rosshandler, Ivan, Lohoff, Tim, Xiang, Yunlong, Hanna, Courtney W, Smallwood, Sebastien, Ibarra-Soria, Ximena, Buettner, Florian, Sanguinetti, Guido, Xie, Wei, Krueger, Felix, Göttgens, Berthold, Rugg-Gunn, Peter J., Kelsey, Gavin, Dean, Wendy, Nichols, Jennifer, Stegle, Oliver, Marioni, John C, Reik, Wolf
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6924995/
https://ncbi.nlm.nih.gov/pubmed/31827285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1825-8
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