Multi-omics profiling of mouse gastrulation at single cell resolution

Formation of the three primary germ layers during gastrulation is an essential step in the establishment of the vertebrate body plan and is associated with major transcriptional changes(1–5). Global epigenetic reprogramming accompanies these changes(6–8), but the role of the epigenome in regulating...

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Published in:Nature
Main Authors: Argelaguet, Ricard, Clark, Stephen J, Mohammed, Hisham, Stapel, L Carine, Krueger, Christel, Kapourani, Chantriolnt-Andreas, Imaz-Rosshandler, Ivan, Lohoff, Tim, Xiang, Yunlong, Hanna, Courtney W, Smallwood, Sebastien, Ibarra-Soria, Ximena, Buettner, Florian, Sanguinetti, Guido, Xie, Wei, Krueger, Felix, Göttgens, Berthold, Rugg-Gunn, Peter J., Kelsey, Gavin, Dean, Wendy, Nichols, Jennifer, Stegle, Oliver, Marioni, John C, Reik, Wolf
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6924995/
https://ncbi.nlm.nih.gov/pubmed/31827285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1825-8
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