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A Bayesian hierarchical model to detect differentially methylated loci from single nucleotide resolution sequencing data
DNA methylation is an important epigenetic modification that has essential roles in cellular processes including gene regulation, development and disease and is widely dysregulated in most types of cancer. Recent advances in sequencing technology have enabled the measurement of DNA methylation at si...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4005660/ https://ncbi.nlm.nih.gov/pubmed/24561809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku154 |
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