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A full Bayesian partition model for identifying hypo- and hyper-methylated loci from single nucleotide resolution sequencing data

BACKGROUD: DNA methylation is an epigenetic modification that plays important roles on gene regulation. Study of whole-genome bisulfite sequencing and reduced representation bisulfite sequencing brings the availability of DNA methylation at single CpG resolution. The main interest of study on DNA me...

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Bibliografische gegevens
Gepubliceerd in:BMC Bioinformatics
Hoofdauteurs: Wang, Henan, He, Chong, Kushwaha, Garima, Xu, Dong, Qiu, Jing
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895387/
https://ncbi.nlm.nih.gov/pubmed/26818685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0850-3
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