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Robust single-cell Hi-C clustering by convolution- and random-walk–based imputation

Three-dimensional genome structure plays a pivotal role in gene regulation and cellular function. Single-cell analysis of genome architecture has been achieved using imaging and chromatin conformation capture methods such as Hi-C. To study variation in chromosome structure between different cell typ...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhou, Jingtian, Ma, Jianzhu, Chen, Yusi, Cheng, Chuankai, Bao, Bokan, Peng, Jian, Sejnowski, Terrence J., Dixon, Jesse R., Ecker, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628819/
https://ncbi.nlm.nih.gov/pubmed/31235599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901423116
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