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Robust single-cell Hi-C clustering by convolution- and random-walk–based imputation
Three-dimensional genome structure plays a pivotal role in gene regulation and cellular function. Single-cell analysis of genome architecture has been achieved using imaging and chromatin conformation capture methods such as Hi-C. To study variation in chromosome structure between different cell typ...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6628819/ https://ncbi.nlm.nih.gov/pubmed/31235599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901423116 |
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