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BRIE: transcriptome-wide splicing quantification in single cells
Single-cell RNA-seq (scRNA-seq) provides a comprehensive measurement of stochasticity in transcription, but the limitations of the technology have prevented its application to dissect variability in RNA processing events such as splicing. Here, we present BRIE (Bayesian regression for isoform estima...
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| Veröffentlicht in: | Genome Biol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5488362/ https://ncbi.nlm.nih.gov/pubmed/28655331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1248-5 |
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