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A Scalable and Accurate Method for Quantifying Vector Genomes of Recombinant Adeno-Associated Viruses in Crude Lysate

Increasing interest and application of recombinant adeno-associated viruses (rAAVs) in basic and clinical research have urged efforts to improve rAAV production quality and yield. Standard vector production workflows call for genome titration of purified vectors at the endpoint of production to asse...

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Pubblicato in:Hum Gene Ther Methods
Autori principali: Ai, Jianzhong, Ibraheim, Raed, Tai, Phillip W.L., Gao, Guangping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488319/
https://ncbi.nlm.nih.gov/pubmed/28488944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2016.173
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