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A Scalable and Accurate Method for Quantifying Vector Genomes of Recombinant Adeno-Associated Viruses in Crude Lysate

Increasing interest and application of recombinant adeno-associated viruses (rAAVs) in basic and clinical research have urged efforts to improve rAAV production quality and yield. Standard vector production workflows call for genome titration of purified vectors at the endpoint of production to asse...

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Bibliografski detalji
Izdano u:Hum Gene Ther Methods
Glavni autori: Ai, Jianzhong, Ibraheim, Raed, Tai, Phillip W.L., Gao, Guangping
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488319/
https://ncbi.nlm.nih.gov/pubmed/28488944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2016.173
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