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A Scalable and Accurate Method for Quantifying Vector Genomes of Recombinant Adeno-Associated Viruses in Crude Lysate

Increasing interest and application of recombinant adeno-associated viruses (rAAVs) in basic and clinical research have urged efforts to improve rAAV production quality and yield. Standard vector production workflows call for genome titration of purified vectors at the endpoint of production to asse...

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Détails bibliographiques
Publié dans:Hum Gene Ther Methods
Auteurs principaux: Ai, Jianzhong, Ibraheim, Raed, Tai, Phillip W.L., Gao, Guangping
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488319/
https://ncbi.nlm.nih.gov/pubmed/28488944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2016.173
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