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Comparative Pharmacodynamics of Telavancin and Vancomycin in the Neutropenic Murine Thigh and Lung Infection Models against Staphylococcus aureus

The pharmacodynamics of telavancin and vancomycin were compared using neutropenic murine thigh and lung infection models. Four Staphylococcus aureus strains were included. The telavancin MIC ranged from 0.06 to 0.25 mg/liter, and the vancomycin MIC ranged from 1 to 4 mg/liter. The plasma pharmacokin...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Lepak, Alexander J., Zhao, Miao, Andes, David R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487664/
https://ncbi.nlm.nih.gov/pubmed/28416551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00281-17
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