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Comparative Pharmacodynamics of Telavancin and Vancomycin in the Neutropenic Murine Thigh and Lung Infection Models against Staphylococcus aureus

The pharmacodynamics of telavancin and vancomycin were compared using neutropenic murine thigh and lung infection models. Four Staphylococcus aureus strains were included. The telavancin MIC ranged from 0.06 to 0.25 mg/liter, and the vancomycin MIC ranged from 1 to 4 mg/liter. The plasma pharmacokin...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Lepak, Alexander J., Zhao, Miao, Andes, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487664/
https://ncbi.nlm.nih.gov/pubmed/28416551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00281-17
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