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Comparative Pharmacodynamics of Telavancin and Vancomycin in the Neutropenic Murine Thigh and Lung Infection Models against Staphylococcus aureus

The pharmacodynamics of telavancin and vancomycin were compared using neutropenic murine thigh and lung infection models. Four Staphylococcus aureus strains were included. The telavancin MIC ranged from 0.06 to 0.25 mg/liter, and the vancomycin MIC ranged from 1 to 4 mg/liter. The plasma pharmacokin...

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Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Lepak, Alexander J., Zhao, Miao, Andes, David R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487664/
https://ncbi.nlm.nih.gov/pubmed/28416551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00281-17
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