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In Vivo Pharmacodynamic Target Assessment of Delafloxacin against Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumoniae in a Murine Lung Infection Model

Delafloxacin is a broad-spectrum anionic fluoroquinolone under development for the treatment of bacterial pneumonia. The goal of the study was to determine the pharmacokinetic/pharmacodynamic (PK/PD) targets in the murine lung infection model for Staphylococcus aureus, Streptococcus pneumoniae, and...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Lepak, Alexander J., Andes, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958193/
https://ncbi.nlm.nih.gov/pubmed/27216072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00647-16
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