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In Vivo Pharmacodynamic Evaluation of Omadacycline against Staphylococcus aureus in the Neutropenic Mouse Pneumonia Model

Omadacycline is an effective therapy for community-acquired bacterial pneumonia (CABP). Given its potent activity against methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant S. aureus (MRSA), we sought to determine the pharmacodynamic activity and target pharmacokinetic/ph...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Lepak, Alexander J., Zhao, Miao, Marchillo, Karen, VanHecker, Jamie, Andes, David R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985749/
https://ncbi.nlm.nih.gov/pubmed/31712210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02058-19
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