Poly(A) tail length regulates PABPC1 expression to tune translation in the heart

The rate of protein synthesis in the adult heart is one of the lowest in mammalian tissues, but it increases substantially in response to stress and hypertrophic stimuli through largely obscure mechanisms. Here, we demonstrate that regulated expression of cytosolic poly(A)-binding protein 1 (PABPC1)...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:eLife
Main Authors: Chorghade, Sandip, Seimetz, Joseph, Emmons, Russell, Yang, Jing, Bresson, Stefan M, Lisio, Michael De, Parise, Gianni, Conrad, Nicholas K, Kalsotra, Auinash
Formáid: Artigo
Teanga:Inglês
Foilsithe: eLife Sciences Publications, Ltd 2017
Ábhair:
Biochemistry
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487213/
https://ncbi.nlm.nih.gov/pubmed/28653618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24139
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla