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The molecular basis of coupling between poly(A)-tail length and translational efficiency

In animal oocytes and early embryos, mRNA poly(A)-tail length strongly influences translational efficiency (TE), but later in development this coupling between tail length and TE disappears. Here, we elucidate how this coupling is first established and why it disappears. Overexpressing cytoplasmic p...

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Publicat a:eLife
Autors principals: Xiang, Kehui, Bartel, David P
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253595/
https://ncbi.nlm.nih.gov/pubmed/34213414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.66493
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