The molecular basis of coupling between poly(A)-tail length and translational efficiency

In animal oocytes and early embryos, mRNA poly(A)-tail length strongly influences translational efficiency (TE), but later in development this coupling between tail length and TE disappears. Here, we elucidate how this coupling is first established and why it disappears. Overexpressing cytoplasmic p...

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Bibliographic Details
Published in:eLife
Main Authors: Xiang, Kehui, Bartel, David P
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2021
Subjects:
Chromosomes and Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253595/
https://ncbi.nlm.nih.gov/pubmed/34213414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.66493
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