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The molecular basis of coupling between poly(A)-tail length and translational efficiency

In animal oocytes and early embryos, mRNA poly(A)-tail length strongly influences translational efficiency (TE), but later in development this coupling between tail length and TE disappears. Here, we elucidate how this coupling is first established and why it disappears. Overexpressing cytoplasmic p...

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Pubblicato in:eLife
Autori principali: Xiang, Kehui, Bartel, David P
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253595/
https://ncbi.nlm.nih.gov/pubmed/34213414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.66493
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