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The molecular basis of coupling between poly(A)-tail length and translational efficiency

In animal oocytes and early embryos, mRNA poly(A)-tail length strongly influences translational efficiency (TE), but later in development this coupling between tail length and TE disappears. Here, we elucidate how this coupling is first established and why it disappears. Overexpressing cytoplasmic p...

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書目詳細資料
發表在:eLife
Main Authors: Xiang, Kehui, Bartel, David P
格式: Artigo
語言:Inglês
出版: eLife Sciences Publications, Ltd 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253595/
https://ncbi.nlm.nih.gov/pubmed/34213414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.66493
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