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Poly(A) tail length regulates PABPC1 expression to tune translation in the heart
The rate of protein synthesis in the adult heart is one of the lowest in mammalian tissues, but it increases substantially in response to stress and hypertrophic stimuli through largely obscure mechanisms. Here, we demonstrate that regulated expression of cytosolic poly(A)-binding protein 1 (PABPC1)...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5487213/ https://ncbi.nlm.nih.gov/pubmed/28653618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24139 |
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