Spinal inflammatory hyperalgesia is mediated by prostaglandin E receptors of the EP2 subtype

Blockade of prostaglandin (PG) production by COX inhibitors is the treatment of choice for inflammatory pain but is also prone to severe side effects. Identification of signaling elements downstream of COX inhibition, particularly of PG receptor subtypes responsible for pain sensitization (hyperalge...

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Vydáno v:J Clin Invest
Hlavní autoři: Reinold, Heiko, Ahmadi, Seifollah, Depner, Ulrike B., Layh, Beate, Heindl, Cornelia, Hamza, May, Pahl, Andreas, Brune, Kay, Narumiya, Shuh, Müller, Ulrike, Zeilhofer, Hanns Ulrich
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2005
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Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548700/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15719070/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI200523618
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