Spinal inflammatory hyperalgesia is mediated by prostaglandin E receptors of the EP2 subtype

Blockade of prostaglandin (PG) production by COX inhibitors is the treatment of choice for inflammatory pain but is also prone to severe side effects. Identification of signaling elements downstream of COX inhibition, particularly of PG receptor subtypes responsible for pain sensitization (hyperalge...

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Autori principali: Reinold, Heiko, Ahmadi, Seifollah, Depner, Ulrike B., Layh, Beate, Heindl, Cornelia, Hamza, May, Pahl, Andreas, Brune, Kay, Narumiya, Shuh, Müller, Ulrike, Zeilhofer, Hanns Ulrich
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC548700/
https://ncbi.nlm.nih.gov/pubmed/15719070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200523618
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