Characterization of EP receptor subtypes responsible for prostaglandin E(2)-induced pain responses by use of EP(1) and EP(3) receptor knockout mice

1. Prostaglandin E(2) (PGE(2)) is known to be the principal pro-inflammatory prostanoid and play an important role in nociception. To identify PGE receptor (EP) subtypes that mediate pain responses to noxious and innocuous stimuli, we studied them by use of EP(1) and EP(3) knockout (EP(1)(−/−) and E...

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Detalhes bibliográficos
Main Authors: Minami, Toshiaki, Nakano, Hiroyuki, Kobayashi, Takuya, Sugimoto, Yukihiko, Ushikubi, Fumitaka, Ichikawa, Atsushi, Narumiya, Shuh, Ito, Seiji
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572799/
https://ncbi.nlm.nih.gov/pubmed/11375261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704092
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