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Characterization of EP receptor subtypes responsible for prostaglandin E(2)-induced pain responses by use of EP(1) and EP(3) receptor knockout mice

1. Prostaglandin E(2) (PGE(2)) is known to be the principal pro-inflammatory prostanoid and play an important role in nociception. To identify PGE receptor (EP) subtypes that mediate pain responses to noxious and innocuous stimuli, we studied them by use of EP(1) and EP(3) knockout (EP(1)(−/−) and E...

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Bibliografiset tiedot
Päätekijät: Minami, Toshiaki, Nakano, Hiroyuki, Kobayashi, Takuya, Sugimoto, Yukihiko, Ushikubi, Fumitaka, Ichikawa, Atsushi, Narumiya, Shuh, Ito, Seiji
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2001
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572799/
https://ncbi.nlm.nih.gov/pubmed/11375261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704092
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