Impaired adrenocorticotropic hormone response to bacterial endotoxin in mice deficient in prostaglandin E receptor EP1 and EP3 subtypes

Sickness evokes various neural responses, one of which is activation of the hypothalamo–pituitary–adrenal (HPA) axis. This response can be induced experimentally by injection of bacterial lipopolysaccharide (LPS) or inflammatory cytokines such as IL-1. Although prostaglandins (PGs) long have been im...

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Detalhes bibliográficos
Main Authors: Matsuoka, Yoko, Furuyashiki, Tomoyuki, Bito, Haruhiko, Ushikubi, Fumitaka, Tanaka, Yasuhiro, Kobayashi, Takuya, Muro, Seiji, Satoh, Noriko, Kayahara, Tetsuro, Higashi, Mikito, Mizoguchi, Akira, Shichi, Hitoshi, Fukuda, Yoshihiro, Nakao, Kazuwa, Narumiya, Shuh
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153060/
https://ncbi.nlm.nih.gov/pubmed/12642666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0633341100
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