The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain

Fragile X syndrome results from the transcriptional silencing of a gene, Fmr1, that codes for an mRNA-binding protein (fragile X mental retardation protein, FMRP) present in neuronal dendrites. FMRP can act as a translational suppressor, and its own translation in dendrites is regulated by group I m...

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Bibliografiska uppgifter
Huvudupphovsmän: Aschrafi, Armaz, Cunningham, Bruce A., Edelman, Gerald M., Vanderklish, Peter W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2005
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC548595/
https://ncbi.nlm.nih.gov/pubmed/15684045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409803102
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