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The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95

Fragile X syndrome (FXS) is a common inherited cause of mental retardation resulting from the absence of the fragile X mental retardation protein (FMRP). FMRP is thought to regulate the translation of target mRNAs, including its own transcript. Here we show that the levels of FMRP are rapidly up-reg...

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Autors principals: Todd, Peter K., Mack, Kenneth J., Malter, James S.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC283599/
https://ncbi.nlm.nih.gov/pubmed/14614133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2336265100
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