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Mechanistic Relationships between Drosophila Fragile X Mental Retardation Protein and Metabotropic Glutamate Receptor A Signaling
Fragile X Syndrome is caused by loss of the FMRP translational regulator. A current hypothesis proposes that FMRP functions downstream of mGluR signaling to regulate synaptic connections. Using the Drosophila disease model, we test relationships between dFMRP and the sole Drosophila mGluR (DmGluRA)...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3989938/ https://ncbi.nlm.nih.gov/pubmed/18280750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2008.01.003 |
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