Mechanistic Relationships between Drosophila Fragile X Mental Retardation Protein and Metabotropic Glutamate Receptor A Signaling

Fragile X Syndrome is caused by loss of the FMRP translational regulator. A current hypothesis proposes that FMRP functions downstream of mGluR signaling to regulate synaptic connections. Using the Drosophila disease model, we test relationships between dFMRP and the sole Drosophila mGluR (DmGluRA)...

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Hlavní autoři: Pan, Luyuan, Woodruff, Elvin, Liang, Ping, Broadie, Kendal
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989938/
https://ncbi.nlm.nih.gov/pubmed/18280750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2008.01.003
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