Metabotropic Glutamate Receptor Activation Regulates Fragile X Mental Retardation Protein and Fmr1 mRNA Localization Differentially in Dendrites and at Synapses

Fragile X syndrome is caused by the absence of the mRNA-binding protein Fragile X mental retardation protein (FMRP), which may play a role in activity-regulated localization and translation of mRNA in dendrites and at synapses. We investigated whether neuronal activity and glutamatergic signals regu...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Antar, Laura N., Afroz, Rownak, Dictenberg, Jason B., Carroll, Reed C., Bassell, Gary J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729525/
https://ncbi.nlm.nih.gov/pubmed/15028757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0099-04.2004
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